The Difference Between Perineural Injection Treatment (PIT) and Corticosteroid Injections

Perineural Injection Therapy (PIT) uses injections of 5% glucose in a saline solution to help relieve pain, to encourage healing and to nourish tissues. 

Doctors often offer Cortisone (steroid) injections for painful regions, so this information provides a comparism in treatments

This information provides a comparism of the 2 different treatment options:

1. Mechanism of Action:

• 5% Glucose: Works by providing nutrients, hydrating tissues, and stimulating the natural healing processes. It enhances the body’s own ability to repair damaged tissues.

• Corticosteroid Injections: Act by suppressing inflammation and the immune response, and providing immediate pain relief.

2. Duration of Effects:

• 5% Glucose: May lead to long-lasting improvements in healing over time. 

• Corticosteroid Injections: Generally, provide quick relief that can last days to months but does not lead to permanent healing.

3. Side Effects:

• 5% Glucose: Typically has few side effects, as glucose is a natural substance in the body.

• Corticosteroid Injections: Can have notable side effects, especially with repeated use, including tissue weakening and systemic effects.

4. Treatment Goals:

• 5% Glucose: Aims to restore function and promote tissue repair for long-term benefits.

• Corticosteroid Injections: Focus on reducing pain and inflammation in the short term.

5. Research and Evidence:

• 5% Glucose: While promising, more extensive research is needed to validate its efficacy and optimal protocols.

• Corticosteroid Injections: Well-researched with established protocols and outcomes, making them a standard treatment option.